No association between polymorphisms in the BDNF gene and age at onset in Huntington disease

BACKGROUND: Recent evidence suggests that brain-derived neurotrophic factor (BDNF) is an attractive candidate for modifying age at onset (AO) in Huntington disease (HD). In particular, the functional Val66Met polymorphism appeared to exert a significant effect. Here we evaluate BDNF variability with...

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Detalles Bibliográficos
Autores principales: Mai, Maren, Akkad, Amer D, Wieczorek, Stefan, Saft, Carsten, Andrich, Jürgen, Kraus, Peter H, Epplen, Jörg T, Arning, Larissa
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1637098/
https://www.ncbi.nlm.nih.gov/pubmed/17096834
http://dx.doi.org/10.1186/1471-2350-7-79

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