Assessment of testicular toxicity in laboratory animals

The currently available methods of assessing testicular toxicity and fertility are discussed. Compounds inducing testicular atrophy mainly affect the seminiferous epithelium, with progressive loss of spermatozoa, spermatids, spermatocytes, and spermatogonia. Quantitative histometric analysis of sper...

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Detalles Bibliográficos
Autores principales: Heywood, Ralph, James, Ronald W.
Formato: Texto
Lenguaje:English
Publicado: 1978
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1637228/
https://www.ncbi.nlm.nih.gov/pubmed/17539158
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author Heywood, Ralph
James, Ronald W.
author_facet Heywood, Ralph
James, Ronald W.
author_sort Heywood, Ralph
collection PubMed
description The currently available methods of assessing testicular toxicity and fertility are discussed. Compounds inducing testicular atrophy mainly affect the seminiferous epithelium, with progressive loss of spermatozoa, spermatids, spermatocytes, and spermatogonia. Quantitative histometric analysis of spermatogenesis, together with hormone assays, could be used to advantage in defining the underlying mechanisms of toxicity.
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spelling pubmed-16372282006-11-17 Assessment of testicular toxicity in laboratory animals Heywood, Ralph James, Ronald W. Environ Health Perspect Articles The currently available methods of assessing testicular toxicity and fertility are discussed. Compounds inducing testicular atrophy mainly affect the seminiferous epithelium, with progressive loss of spermatozoa, spermatids, spermatocytes, and spermatogonia. Quantitative histometric analysis of spermatogenesis, together with hormone assays, could be used to advantage in defining the underlying mechanisms of toxicity. 1978-06 /pmc/articles/PMC1637228/ /pubmed/17539158 Text en
spellingShingle Articles
Heywood, Ralph
James, Ronald W.
Assessment of testicular toxicity in laboratory animals
title Assessment of testicular toxicity in laboratory animals
title_full Assessment of testicular toxicity in laboratory animals
title_fullStr Assessment of testicular toxicity in laboratory animals
title_full_unstemmed Assessment of testicular toxicity in laboratory animals
title_short Assessment of testicular toxicity in laboratory animals
title_sort assessment of testicular toxicity in laboratory animals
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1637228/
https://www.ncbi.nlm.nih.gov/pubmed/17539158
work_keys_str_mv AT heywoodralph assessmentoftesticulartoxicityinlaboratoryanimals
AT jamesronaldw assessmentoftesticulartoxicityinlaboratoryanimals

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