Cadmium, an effector in the synthesis of thionein.

Cadmium can elicit the synthesis of thionein in liver cells independent of tissue-organ interactions. The metal diffuses across the plasma membrane and is partitioned between subcellular components in a time dependent manner such that thionein synthesis responds to levels of nonspecifically and spec...

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Detalles Bibliográficos
Autores principales: Bryan, S E, Hidalgo, H A, Koppa, V, Smith, H A
Formato: Texto
Lenguaje:English
Publicado: 1979
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1637499/
https://www.ncbi.nlm.nih.gov/pubmed/488043
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author Bryan, S E
Hidalgo, H A
Koppa, V
Smith, H A
author_facet Bryan, S E
Hidalgo, H A
Koppa, V
Smith, H A
author_sort Bryan, S E
collection PubMed
description Cadmium can elicit the synthesis of thionein in liver cells independent of tissue-organ interactions. The metal diffuses across the plasma membrane and is partitioned between subcellular components in a time dependent manner such that thionein synthesis responds to levels of nonspecifically and specifically bound cytoplasmic metal. Cadmium appears to function at the transcriptional level, and the metal may act to increase the pool of specific m-RNA's.
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spelling pubmed-16374992006-11-17 Cadmium, an effector in the synthesis of thionein. Bryan, S E Hidalgo, H A Koppa, V Smith, H A Environ Health Perspect Research Article Cadmium can elicit the synthesis of thionein in liver cells independent of tissue-organ interactions. The metal diffuses across the plasma membrane and is partitioned between subcellular components in a time dependent manner such that thionein synthesis responds to levels of nonspecifically and specifically bound cytoplasmic metal. Cadmium appears to function at the transcriptional level, and the metal may act to increase the pool of specific m-RNA's. 1979-02 /pmc/articles/PMC1637499/ /pubmed/488043 Text en
spellingShingle Research Article
Bryan, S E
Hidalgo, H A
Koppa, V
Smith, H A
Cadmium, an effector in the synthesis of thionein.
title Cadmium, an effector in the synthesis of thionein.
title_full Cadmium, an effector in the synthesis of thionein.
title_fullStr Cadmium, an effector in the synthesis of thionein.
title_full_unstemmed Cadmium, an effector in the synthesis of thionein.
title_short Cadmium, an effector in the synthesis of thionein.
title_sort cadmium, an effector in the synthesis of thionein.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1637499/
https://www.ncbi.nlm.nih.gov/pubmed/488043
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AT koppav cadmiumaneffectorinthesynthesisofthionein
AT smithha cadmiumaneffectorinthesynthesisofthionein

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