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Physiologically based pharmacokinetic models for trichloroethylene and its oxidative metabolites.
Trichloroethylene (TCE) pharmacokinetics have been studied in experimental animals and humans for over 30 years. Compartmental and physiologically based pharmacokinetic (PBPK) models have been developed for the uptake, distribution, and metabolism of TCE and the production, distribution, metabolism,...
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2000
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1637763/ https://www.ncbi.nlm.nih.gov/pubmed/10807557 |