Cargando…

Physiologically based pharmacokinetic models for trichloroethylene and its oxidative metabolites.

Trichloroethylene (TCE) pharmacokinetics have been studied in experimental animals and humans for over 30 years. Compartmental and physiologically based pharmacokinetic (PBPK) models have been developed for the uptake, distribution, and metabolism of TCE and the production, distribution, metabolism,...

Descripción completa

Detalles Bibliográficos
Autor principal:	Fisher, J W
Formato:	Texto
Lenguaje:	English
Publicado:	2000
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1637763/ https://www.ncbi.nlm.nih.gov/pubmed/10807557

Ejemplares similares

Issues in the Pharmacokinetics of Trichloroethylene and Its Metabolites
por: Chiu, Weihsueh A., et al.
Publicado: (2006)

Development of a physiologically based pharmacokinetic model of trichloroethylene and its metabolites for use in risk assessment.
por: Clewell, H J, et al.
Publicado: (2000)

Mutagenicity of trichloroethylene and its metabolites: implications for the risk assessment of trichloroethylene.
por: Moore, M M, et al.
Publicado: (2000)

Physiologically Based Pharmacokinetic (PBPK) Modeling of Interstrain Variability in Trichloroethylene Metabolism in the Mouse
por: Chiu, Weihsueh A., et al.
Publicado: (2014)

Metabolism of trichloroethylene.
por: Lash, L H, et al.
Publicado: (2000)

Neurotoxic and pharmacokinetic responses to trichloroethylene as a function of exposure scenario.
por: Boyes, W K, et al.
Publicado: (2000)

Mode of action of liver tumor induction by trichloroethylene and its metabolites, trichloroacetate and dichloroacetate.
por: Bull, R J
Publicado: (2000)

A review: trichloroethylene metabolites: potential cardiac teratogens.
por: Johnson, P D, et al.
Publicado: (1998)

Trichloroethylene Hypersensitivity Syndrome Is Potentially Mediated through Its Metabolite Chloral Hydrate
por: Huang, Yongshun, et al.
Publicado: (2015)

Trichloroethylene and Its Oxidative Metabolites Enhance the Activated State and Th1 Cytokine Gene Expression inJurkat Cells
por: Pan, Yao, et al.
Publicado: (2015)

Physiologically‐based pharmacokinetic modeling of remdesivir and its metabolites in pregnant women with COVID‐19
por: Liu, Xiaomei I., et al.
Publicado: (2022)

Exposure assessment of trichloroethylene.
por: Wu, C, et al.
Publicado: (2000)

Carcinogenicity of Trichloroethylene
por: Wartenberg, D
Publicado: (2002)

Reproductive toxicology. Trichloroethylene.
Publicado: (1997)

Reproductive toxicology. Trichloroethylene.
Publicado: (1997)

Human variability and susceptibility to trichloroethylene.
por: Pastino, G M, et al.
Publicado: (2000)

Key Issues in the Modes of Action and Effects of Trichloroethylene Metabolites for Liver and Kidney Tumorigenesis
por: Caldwell, Jane C., et al.
Publicado: (2006)

Biologically based dose-response model for liver tumors induced by trichloroethylene.
por: Chen, C W
Publicado: (2000)

Exposure reconstruction of trichloroethylene among patients with occupational trichloroethylene hypersensitivity syndrome
por: NAKAJIMA, Tamie, et al.
Publicado: (2018)

Phytoremediation of trichloroethylene with hybrid poplars.
por: Gordon, M, et al.
Publicado: (1998)

Trichloroethylene and Cardiac Malformations
por: Hardin, Bryan D., et al.
Publicado: (2004)

A Physiologically Based Pharmacokinetic Model of Ketoconazole and Its Metabolites as Drug–Drug Interaction Perpetrators
por: Marok, Fatima Zahra, et al.
Publicado: (2023)

Unraveling bisphenol A pharmacokinetics using physiologically based pharmacokinetic modeling
por: Yang, Xiaoxia, et al.
Publicado: (2015)

Trichloroethylene and cancer: epidemiologic evidence.
por: Wartenberg, D, et al.
Publicado: (2000)

A physiologically-based pharmacokinetic model of oseltamivir phosphate and its carboxylate metabolite for rats and humans
por: Gao, Guanghua, et al.
Publicado: (2019)

Trichloroethylene health risks--state of the science.
por: Scott, C S, et al.
Publicado: (2000)

Modes of action of trichloroethylene for kidney tumorigenesis.
por: Lash, L H, et al.
Publicado: (2000)

Pharmacokinetic Characterization of Supinoxin and Its Physiologically Based Pharmacokinetic Modeling in Rats
por: Song, Yoo-Kyung, et al.
Publicado: (2021)

Metabolism of trichloroethylene and tetrachloroethylene in human subjects.
por: Ikeda, M
Publicado: (1977)

Trichloroethylene: Johnson et al.’s Response
por: Johnson, Paula D., et al.
Publicado: (2004)

Physiologically Based Pharmacokinetic Modeling of Transdermal Selegiline and Its Metabolites for the Evaluation of Disposition Differences between Healthy and Special Populations
por: Puttrevu, Santosh Kumar, et al.
Publicado: (2020)

Prediction of Drug–Drug–Gene Interaction Scenarios of (E)-Clomiphene and Its Metabolites Using Physiologically Based Pharmacokinetic Modeling
por: Kovar, Christina, et al.
Publicado: (2022)

Carbon Nanotube Based Groundwater Remediation: The Case of Trichloroethylene
por: Jha, Kshitij C., et al.
Publicado: (2016)

Influence of the synthesis method on the catalytic activity of mayenite for the oxidation of gas-phase trichloroethylene
por: Intiso, Adriano, et al.
Publicado: (2019)

Statistical analysis of Fisher et al. PBPK model of trichloroethylene kinetics.
por: Bois, F Y
Publicado: (2000)

Statistical analysis of Clewell et al. PBPK model of trichloroethylene kinetics.
por: Bois, F Y
Publicado: (2000)

Trichloroethylene: An Invisible Cause of Parkinson’s Disease?
por: Dorsey, E. Ray, et al.
Publicado: (2023)

Human physiologically based pharmacokinetic model for propofol
por: Levitt, David G, et al.
Publicado: (2005)

Application of Physiologically Based Pharmacokinetic Models in Chemical Risk Assessment
por: Mumtaz, Moiz, et al.
Publicado: (2012)

Dioxinlike properties of a trichloroethylene combustion-generated aerosol.
por: Villalobos, S A, et al.
Publicado: (1996)

Cannot write session to /tmp/vufind_sessions/sess_gvo1cghb1s656cb23uqi6j298v