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Low-level exposure to methylmercury modifies muscarinic cholinergic receptor binding characteristics in rat brain and lymphocytes: physiologic implications and new opportunities in biologic monitoring.
Methylmercury (MeHg) affects several parameters of cholinergic function. These alterations are thought to play a role in MeHg neurotoxicity. In vitro experiments have indicated that MeHg acts as a strong competitive inhibitor of radioligand binding to muscarinic cholinergic receptors (mAChRs) in rat...
Autores principales: | Coccini, T, Randine, G, Candura, S M, Nappi, R E, Prockop, L D, Manzo, L |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1637867/ https://www.ncbi.nlm.nih.gov/pubmed/10620521 |
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