The expansion of CD4(+)CD28(- )T cells in patients with rheumatoid arthritis

Clonal expansion of CD4(+)CD28(- )T cells is a characteristic finding in patients with rheumatoid arthritis (RA). Expanded CD4(+ )clonotypes are present in the peripheral blood, infiltrate into the joints, and persist for years. CD4(+)CD28(- )T cells are oligoclonal lymphocytes that are rare in heal...

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Detalles Bibliográficos
Autores principales: Pawlik, Andrzej, Ostanek, Lidia, Brzosko, Iwona, Brzosko, Marek, Masiuk, Marek, Machalinski, Boguslaw, Gawronska-Szklarz, Barbara
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC165060/
https://www.ncbi.nlm.nih.gov/pubmed/12823856
http://dx.doi.org/10.1186/ar766