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The centrosome and cell proliferation

Centrosomes are frequently amplified in cancer cells. Increased numbers of centrosomes can give rise to multipolar spindles in mitosis, and thereby lead to the formation of aneuploid daughter cells. However, whether centrosome amplification is a cause or a consequence of cancer is unclear. In contra...

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Detalles Bibliográficos
Autores principales: Srsen, Vlastimil, Merdes, Andreas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1654144/
https://www.ncbi.nlm.nih.gov/pubmed/17109756
http://dx.doi.org/10.1186/1747-1028-1-26

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