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Mitochondrial oxidative stress and nitrate tolerance – comparison of nitroglycerin and pentaerithrityl tetranitrate in Mn-SOD(+/- )mice

BACKGROUND: Chronic therapy with nitroglycerin (GTN) results in a rapid development of nitrate tolerance which is associated with an increased production of reactive oxygen species (ROS). According to recent studies, mitochondrial ROS formation and oxidative inactivation of the organic nitrate bioac...

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Detalles Bibliográficos
Autores principales:	Mollnau, Hanke, Wenzel, Philip, Oelze, Matthias, Treiber, Nicolai, Pautz, Andrea, Schulz, Eberhard, Schuhmacher, Swenja, Reifenberg, Kurt, Stalleicken, Dirk, Scharffetter-Kochanek, Karin, Kleinert, Hartmut, Münzel, Thomas, Daiber, Andreas
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1654181/ https://www.ncbi.nlm.nih.gov/pubmed/17092343 http://dx.doi.org/10.1186/1471-2261-6-44

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