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Novel metaheuristic for parameter estimation in nonlinear dynamic biological systems

BACKGROUND: We consider the problem of parameter estimation (model calibration) in nonlinear dynamic models of biological systems. Due to the frequent ill-conditioning and multi-modality of many of these problems, traditional local methods usually fail (unless initialized with very good guesses of t...

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Detalles Bibliográficos
Autores principales: Rodriguez-Fernandez, Maria, Egea, Jose A, Banga, Julio R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1654195/
https://www.ncbi.nlm.nih.gov/pubmed/17081289
http://dx.doi.org/10.1186/1471-2105-7-483