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Novel metaheuristic for parameter estimation in nonlinear dynamic biological systems
BACKGROUND: We consider the problem of parameter estimation (model calibration) in nonlinear dynamic models of biological systems. Due to the frequent ill-conditioning and multi-modality of many of these problems, traditional local methods usually fail (unless initialized with very good guesses of t...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1654195/ https://www.ncbi.nlm.nih.gov/pubmed/17081289 http://dx.doi.org/10.1186/1471-2105-7-483 |