Cargando…
Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions
BACKGROUND: The PE and PPE multigene families of Mycobacterium tuberculosis comprise about 10% of the coding potential of the genome. The function of the proteins encoded by these large gene families remains unknown, although they have been proposed to be involved in antigenic variation and disease...
Autores principales: | Gey van Pittius, Nicolaas C, Sampson, Samantha L, Lee, Hyeyoung, Kim, Yeun, van Helden, Paul D, Warren, Robin M |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1660551/ https://www.ncbi.nlm.nih.gov/pubmed/17105670 http://dx.doi.org/10.1186/1471-2148-6-95 |
Ejemplares similares
-
The plasmid-mediated evolution of the mycobacterial ESX (Type VII) secretion systems
por: Newton-Foot, Mae, et al.
Publicado: (2016) -
Comparative Analysis of Mycobacterium tuberculosis pe and ppe Genes Reveals High Sequence Variation and an Apparent Absence of Selective Constraints
por: McEvoy, Christopher R. E., et al.
Publicado: (2012) -
Two promoters in the esx-3 gene cluster of Mycobacterium smegmatis respond inversely to different iron concentrations in vitro
por: Fang, Zhuo, et al.
Publicado: (2017) -
Evidence for a rapid rate of molecular evolution at the hypervariable and immunogenic Mycobacterium tuberculosis PPE38 gene region
por: McEvoy, Christopher RE, et al.
Publicado: (2009) -
Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages
por: Phelan, Jody E., et al.
Publicado: (2016)