Molecular surveillance of the antifolate-resistant mutation I164L in imported african isolates of Plasmodium falciparum in Europe: sentinel data from TropNetEurop

BACKGROUND: Malaria parasites that carry the DHFR-mutation I164L are not only highly resistant to sulfadoxine-pyrimethamine but also to the new antimalarial drug chlorproguanil-dapsone. The spread of this mutation in Africa would result in a public health disaster since there is a lack of effective...

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Detalles Bibliográficos
Autores principales: Wichmann, Ole, Jelinek, Tomas, Peyerl-Hoffmann, Gabriele, Mühlberger, Nikolai, Grobusch, Martin P, Gascon, Joaquim, Matteelli, Alberto, Hatz, Christoph, Laferl, Hermann, Schulze, Marco, Burchard, Gerd, Cunha, Saraiva da, Beran, Jiøi, McWhinney, Paul, Kollaritsch, Herwig, Kern, Peter, Cuadros, Juan, Alifrangis, Michael, Gjørup, Ida
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC166141/
https://www.ncbi.nlm.nih.gov/pubmed/12869209
http://dx.doi.org/10.1186/1475-2875-2-17

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