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Elective open abdominal aortic aneurysm repair: a seven-year experience

INTRODUCTION: The seven-year experience of elective abdominal aortic aneurysm (AAA) repair of a vascular surgical unit in a teaching hospital was reviewed to determine the factors associated with in-hospital mortality. METHODS: All patients who underwent elective open repair of an AAA between July 1...

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Autores principales: Mackenzie, Stuart, Swan, Judith R, D'Este, Cate, Spigelman, Allan D
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1661605/
https://www.ncbi.nlm.nih.gov/pubmed/18360540
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author Mackenzie, Stuart
Swan, Judith R
D'Este, Cate
Spigelman, Allan D
author_facet Mackenzie, Stuart
Swan, Judith R
D'Este, Cate
Spigelman, Allan D
author_sort Mackenzie, Stuart
collection PubMed
description INTRODUCTION: The seven-year experience of elective abdominal aortic aneurysm (AAA) repair of a vascular surgical unit in a teaching hospital was reviewed to determine the factors associated with in-hospital mortality. METHODS: All patients who underwent elective open repair of an AAA between July 1, 1991, and June 30, 1998, were identified using International Classification of Diseases Ninth Revision (ICD-9) codes. Twenty-four variables were selected for investigation by reviewing the published literature and by discussion with local vascular surgeons. Data were obtained by retrospective medical record review. Variables were first analysed by univariate analysis, and those with a p-value up to 0.25 were included in multivariate analysis. RESULTS: Of the 219 patients reviewed, 8 (3.7%, 95% confidence interval, 1.6%, 7.1%) died during the admission. The mean age of patients was 69.9 years, and 81% of them were male. Univariate analysis found that female sex, renal artery involvement in the aneurysm, and aortic cross-clamp duration of 90 min or greater were significantly associated with mortality. Multivariate analysis found that female sex, use of a bifurcated graft, and performance of an additional procedure at the time of operation were the only variables independently associated with mortality. DISCUSSION: Use of a bifurcated graft was a significant prognostic variable on logistic regression analysis confirming that the technical difficulty of the operation and the morphology of the aneurysm are important factors in determining mortality. Why women may be at higher risk for death is unclear. This study also highlights that caution is required when interpreting raw audit data.
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spelling pubmed-16616052008-03-21 Elective open abdominal aortic aneurysm repair: a seven-year experience Mackenzie, Stuart Swan, Judith R D'Este, Cate Spigelman, Allan D Ther Clin Risk Manag Original Research INTRODUCTION: The seven-year experience of elective abdominal aortic aneurysm (AAA) repair of a vascular surgical unit in a teaching hospital was reviewed to determine the factors associated with in-hospital mortality. METHODS: All patients who underwent elective open repair of an AAA between July 1, 1991, and June 30, 1998, were identified using International Classification of Diseases Ninth Revision (ICD-9) codes. Twenty-four variables were selected for investigation by reviewing the published literature and by discussion with local vascular surgeons. Data were obtained by retrospective medical record review. Variables were first analysed by univariate analysis, and those with a p-value up to 0.25 were included in multivariate analysis. RESULTS: Of the 219 patients reviewed, 8 (3.7%, 95% confidence interval, 1.6%, 7.1%) died during the admission. The mean age of patients was 69.9 years, and 81% of them were male. Univariate analysis found that female sex, renal artery involvement in the aneurysm, and aortic cross-clamp duration of 90 min or greater were significantly associated with mortality. Multivariate analysis found that female sex, use of a bifurcated graft, and performance of an additional procedure at the time of operation were the only variables independently associated with mortality. DISCUSSION: Use of a bifurcated graft was a significant prognostic variable on logistic regression analysis confirming that the technical difficulty of the operation and the morphology of the aneurysm are important factors in determining mortality. Why women may be at higher risk for death is unclear. This study also highlights that caution is required when interpreting raw audit data. Dove Medical Press 2005-03 2005-03 /pmc/articles/PMC1661605/ /pubmed/18360540 Text en © 2005 Dove Medical Press Limited. All rights reserved
spellingShingle Original Research
Mackenzie, Stuart
Swan, Judith R
D'Este, Cate
Spigelman, Allan D
Elective open abdominal aortic aneurysm repair: a seven-year experience
title Elective open abdominal aortic aneurysm repair: a seven-year experience
title_full Elective open abdominal aortic aneurysm repair: a seven-year experience
title_fullStr Elective open abdominal aortic aneurysm repair: a seven-year experience
title_full_unstemmed Elective open abdominal aortic aneurysm repair: a seven-year experience
title_short Elective open abdominal aortic aneurysm repair: a seven-year experience
title_sort elective open abdominal aortic aneurysm repair: a seven-year experience
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1661605/
https://www.ncbi.nlm.nih.gov/pubmed/18360540
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