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Is telomerase reactivation associated with the down-regulation of TGF β receptor-II expression in human breast cancer?
BACKGROUND: Telomerase is a ribonucleoprotein that synthesizes telomeres and plays an important role in chromosomal stability and cellular immortalisation. Telomerase activity is detectable in most human cancers but not in normal somatic cells. TGF beta (transforming growth factor beta) is a member...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC166282/ https://www.ncbi.nlm.nih.gov/pubmed/12877749 http://dx.doi.org/10.1186/1475-2867-3-9 |