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In silico and microarray-based genomic approaches to identifying potential vaccine candidates against Leptospira interrogans

BACKGROUND: Currently available vaccines against leptospirosis are of low efficacy, have an unacceptable side-effect profile, do not induce long-term protection, and provide no cross-protection against the different serovars of pathogenic leptospira. The current major focus in leptospirosis research...

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Detalles Bibliográficos
Autores principales: Yang, Hong-Liang, Zhu, Yong-Zhang, Qin, Jin-Hong, He, Ping, Jiang, Xu-Cheng, Zhao, Guo-Ping, Guo, Xiao-Kui
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1664576/
https://www.ncbi.nlm.nih.gov/pubmed/17109759
http://dx.doi.org/10.1186/1471-2164-7-293