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HIV-1 Vpr-Induced Apoptosis Is Cell Cycle Dependent and Requires Bax but Not ANT

The HIV-1 accessory protein viral protein R (Vpr) causes G(2) arrest and apoptosis in infected cells. We previously identified the DNA damage–signaling protein ATR as the cellular factor that mediates Vpr-induced G(2) arrest and apoptosis. Here, we examine the mechanism of induction of apoptosis by...

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Detalles Bibliográficos
Autores principales:	Andersen, Joshua L, DeHart, Jason L, Zimmerman, Erik S, Ardon, Orly, Kim, Baek, Jacquot, Guillaume, Benichou, Serge, Planelles, Vicente
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1665652/ https://www.ncbi.nlm.nih.gov/pubmed/17140287 http://dx.doi.org/10.1371/journal.ppat.0020127

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