Heparanase deglycanation of syndecan-1 is required for binding of the epithelial-restricted prosecretory mitogen lacritin

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Cell surface heparan sulfate (HS) proteoglycans are carbohydrate-rich regulators of cell migratory, mitogenic, secretory, and inflammatory activity that bind and present soluble heparin-binding growth factors (e.g., fibroblast growth factor, Wnt, Hh, transforming growth factor β, amphiregulin, and h...

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Detalles Bibliográficos
Autores principales: Ma, Peisong, Beck, Shannon L., Raab, Ronald W., McKown, Robert L., Coffman, George L., Utani, Atsushi, Chirico, William J., Rapraeger, Alan C., Laurie, Gordon W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1666580/
https://www.ncbi.nlm.nih.gov/pubmed/16982797
http://dx.doi.org/10.1083/jcb.200511134
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