Cargando…

A microfluidic-FCS platform for investigation on the dissociation of Sp1-DNA complex by doxorubicin

The transcription factor (TF) Sp1 is a well-known RNA polymerase II transcription activator that binds to GC-rich recognition sites in a number of essential cellular and viral promoters. In addition, direct interference of Sp1 binding to DNA cognate sites using DNA-interacting compounds may provide...

Descripción completa

Detalles Bibliográficos
Autores principales: Yeh, Hsin-Chih, Puleo, Christopher M., Lim, Teck Chuan, Ho, Yi-Ping, Giza, Paul E., Huang, Ru Chih C., Wang, Tza-Huei
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1669725/
https://www.ncbi.nlm.nih.gov/pubmed/17108358
http://dx.doi.org/10.1093/nar/gkl787

Ejemplares similares