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The telomerase-recruitment domain of the telomere binding protein Cdc13 is regulated by Mec1p/Tel1p-dependent phosphorylation

The DNA damage-responsive protein kinases ATM and ATR phosphorylate SQ/TQ motifs that lie in clusters in most of their in vivo targets. Budding yeast Cdc13p contains two clusters of SQ/TQ motifs, suggesting that it might be a target of Mec1p/Tel1p (yeast ATR/ATM). Here we demonstrated that the telom...

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Detalles Bibliográficos
Autores principales: Tseng, Shun-Fu, Lin, Jing-Jer, Teng, Shu-Chun
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1669766/
https://www.ncbi.nlm.nih.gov/pubmed/17108359
http://dx.doi.org/10.1093/nar/gkl786