A self-inactivating retrovector incorporating the IL-2 promoter for activation-induced transgene expression in genetically engineered T-cells

BACKGROUND: T-cell activation leads to signaling pathways that ultimately result in induction of gene transcription from the interleukin-2 (IL-2) promoter. We hypothesized that the IL-2 promoter or its synthetic derivatives can lead to T-cell specific, activation-induced transgene expression. Our ob...

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Detalles Bibliográficos
Autores principales: Jaalouk, Diana E, Lejeune, Laurence, Couture, Clément, Galipeau, Jacques
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1679806/
https://www.ncbi.nlm.nih.gov/pubmed/17118192
http://dx.doi.org/10.1186/1743-422X-3-97

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1679806/
https://www.ncbi.nlm.nih.gov/pubmed/17118192
http://dx.doi.org/10.1186/1743-422X-3-97

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