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Gene expression profiling following constitutive activation of MEK1 and transformation of rat intestinal epithelial cells

BACKGROUND: Constitutive activation of MEK1 (caMEK) can induce the oncogenic transformation of normal intestinal epithelial cells. To define the genetic changes that occur during this process, we used oligonucleotide microarrays to determine which genes are regulated following the constitutive activ...

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Detalles Bibliográficos
Autores principales: Komatsu, Koga, Buchanan, F Gregory, Otaka, Michiro, Jin, Mario, Odashima, Masaru, Horikawa, Yohei, Watanabe, Sumio, DuBois, Raymond N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1679808/
https://www.ncbi.nlm.nih.gov/pubmed/17112382
http://dx.doi.org/10.1186/1476-4598-5-63