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Gene expression profiling following constitutive activation of MEK1 and transformation of rat intestinal epithelial cells
BACKGROUND: Constitutive activation of MEK1 (caMEK) can induce the oncogenic transformation of normal intestinal epithelial cells. To define the genetic changes that occur during this process, we used oligonucleotide microarrays to determine which genes are regulated following the constitutive activ...
Autores principales: | Komatsu, Koga, Buchanan, F Gregory, Otaka, Michiro, Jin, Mario, Odashima, Masaru, Horikawa, Yohei, Watanabe, Sumio, DuBois, Raymond N |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1679808/ https://www.ncbi.nlm.nih.gov/pubmed/17112382 http://dx.doi.org/10.1186/1476-4598-5-63 |
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