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Global analysis of gene function in yeast by quantitative phenotypic profiling

We present a method for the global analysis of the function of genes in budding yeast based on hierarchical clustering of the quantitative sensitivity profiles of the 4756 strains with individual homozygous deletion of nonessential genes to a broad range of cytotoxic or cytostatic agents. This metho...

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Detalles Bibliográficos
Autores principales:	Brown, James A, Sherlock, Gavin, Myers, Chad L, Burrows, Nicola M, Deng, Changchun, Wu, H Irene, McCann, Kelly E, Troyanskaya, Olga G, Brown, J Martin
Formato:	Texto
Lenguaje:	English
Publicado:	2006
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1681475/ https://www.ncbi.nlm.nih.gov/pubmed/16738548 http://dx.doi.org/10.1038/msb4100043

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