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Core transcriptional regulatory circuitry in human hepatocytes
We mapped the transcriptional regulatory circuitry for six master regulators in human hepatocytes using chromatin immunoprecipitation and high-resolution promoter microarrays. The results show that these regulators form a highly interconnected core circuitry, and reveal the local regulatory network...
Autores principales: | Odom, Duncan T, Dowell, Robin D, Jacobsen, Elizabeth S, Nekludova, Lena, Rolfe, P Alexander, Danford, Timothy W, Gifford, David K, Fraenkel, Ernest, Bell, Graeme I, Young, Richard A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1681491/ https://www.ncbi.nlm.nih.gov/pubmed/16738562 http://dx.doi.org/10.1038/msb4100059 |
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