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Oscillations and variability in the p53 system

Understanding the dynamics and variability of protein circuitry requires accurate measurements in living cells as well as theoretical models. To address this, we employed one of the best-studied protein circuits in human cells, the negative feedback loop between the tumor suppressor p53 and the onco...

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Detalles Bibliográficos
Autores principales: Geva-Zatorsky, Naama, Rosenfeld, Nitzan, Itzkovitz, Shalev, Milo, Ron, Sigal, Alex, Dekel, Erez, Yarnitzky, Talia, Liron, Yuvalal, Polak, Paz, Lahav, Galit, Alon, Uri
Formato: Texto
Lenguaje:English
Publicado: 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1681500/
https://www.ncbi.nlm.nih.gov/pubmed/16773083
http://dx.doi.org/10.1038/msb4100068