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Noise in transcription negative feedback loops: simulation and experimental analysis
Negative feedback loops have been invoked as a way to control and decrease transcriptional noise. Here, we have built three circuits to test the effect of negative feedback loops on transcriptional noise of an autoregulated gene encoding a transcription factor (TF) and a downstream gene (DG), regula...
Autores principales: | Dublanche, Yann, Michalodimitrakis, Konstantinos, Kümmerer, Nico, Foglierini, Mathilde, Serrano, Luis |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1681513/ https://www.ncbi.nlm.nih.gov/pubmed/16883354 http://dx.doi.org/10.1038/msb4100081 |
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