Sensory defects in Necdin deficient mice result from a loss of sensory neurons correlated within an increase of developmental programmed cell death

BACKGROUND: The human NECDIN gene is involved in a neurodevelopmental disorder, Prader-Willi syndrome (PWS). Previously we reported a mouse Necdin knock-out model with similar defects to PWS patients. Despite the putative roles attributed to Necdin, mainly from in vitro studies, its in vivo function...

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Detalles Bibliográficos
Autores principales: Andrieu, David, Meziane, Hamid, Marly, Fabienne, Angelats, Corinne, Fernandez, Pierre-Alain, Muscatelli, Françoise
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1687209/
https://www.ncbi.nlm.nih.gov/pubmed/17116257
http://dx.doi.org/10.1186/1471-213X-6-56

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1687209/
https://www.ncbi.nlm.nih.gov/pubmed/17116257
http://dx.doi.org/10.1186/1471-213X-6-56

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