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Chromosomal integration of LTR-flanked DNA in yeast expressing HIV-1 integrase: down regulation by RAD51
HIV-1 integrase (IN) is the key enzyme catalyzing the proviral DNA integration step. Although the enzyme catalyzes the integration step accurately in vitro, whether IN is sufficient for in vivo integration and how it interacts with the cellular machinery remains unclear. We set up a yeast cellular i...
Autores principales: | Desfarges, S., San Filippo, J., Fournier, M., Calmels, C., Caumont-Sarcos, A., Litvak, S., Sung, P., Parissi, V. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1693895/ https://www.ncbi.nlm.nih.gov/pubmed/17090598 http://dx.doi.org/10.1093/nar/gkl843 |
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