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ATM mediates oxidative stress-induced dephosphorylation of DNA ligase IIIα

Among the three mammalian genes encoding DNA ligases, only the LIG3 gene does not have a homolog in lower eukaryotes. In somatic mammalian cells, the nuclear form of DNA ligase IIIα forms a stable complex with the DNA repair protein XRCC1 that is also found only in higher eukaryotes. Recent studies...

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Detalles Bibliográficos
Autores principales:	Dong, Zhiwan, Tomkinson, Alan E.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2006
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1694025/ https://www.ncbi.nlm.nih.gov/pubmed/17040896 http://dx.doi.org/10.1093/nar/gkl705

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