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Small interfering RNA targeted to stem-loop II of the 5' untranslated region effectively inhibits expression of six HCV genotypes

BACKGROUND: The antiviral action of interferon alpha targets the 5' untranslated region (UTR) used by hepatitis C virus (HCV) to translate protein by an internal ribosome entry site (IRES) mechanism. Although this sequence is highly conserved among different clinical strains, approximately half...

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Detalles Bibliográficos
Autores principales:	Prabhu, Ramesh, Garry, Robert F, Dash, Srikanta
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1698915/ https://www.ncbi.nlm.nih.gov/pubmed/17129382 http://dx.doi.org/10.1186/1743-422X-3-100

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