Cargando…

Nef-mediated TCR-CD3 and MHC-I down-modulation prevents CD4+ T cell depletion in natural SIV infection

Detalles Bibliográficos
Autores principales:	Schindler, Michael, Münch, Jan, Kutsch, Olaf, Li, Hui, Santiago, Mario L, Bibollet-Ruche, Frederic, Müller-Trutwin, Michaela C, Novembre, Francis J, Peeters, Martine, Courgnaud, Valerie, Bailes, Elizabeth, Roques, Pierre, Sodora, Donald L, Sharp, Paul, Silvestri, Guido, Hahn, Beatrice H, Kirchhoff, Frank
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Oral Presentation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1717010/ http://dx.doi.org/10.1186/1742-4690-3-S1-S95

Ejemplares similares

Inefficient Nef-Mediated Downmodulation of CD3 and MHC-I Correlates with Loss of CD4(+) T Cells in Natural SIV Infection
por: Schindler, Michael, et al.
Publicado: (2008)

Nef-Mediated CD3-TCR Downmodulation Dampens Acute Inflammation and Promotes SIV Immune Evasion
por: Joas, Simone, et al.
Publicado: (2020)

Conservation of Nef function across highly diverse lineages of SIVsmm
por: Schmökel, Jan, et al.
Publicado: (2009)

Mutation of a diacidic motif in SIV-PBj Nef impairs T-cell activation and enteropathic disease
por: Tschulena, Ulrich, et al.
Publicado: (2011)

Link between Primate Lentiviral Coreceptor Usage and Nef Function
por: Schmökel, Jan, et al.
Publicado: (2013)

Maturation of protective immunity induced by SIVΔnef correlates with differential expression of transcription factors in SIV-specific CD8+ T cells
por: Billingsley, JM, et al.
Publicado: (2012)

Transduction of SIV-Specific TCR Genes into Rhesus Macaque CD8(+) T Cells Conveys the Ability to Suppress SIV Replication
por: Barsov, Eugene V., et al.
Publicado: (2011)

Nef interferes with development of thymic T cell precursors: differential mechanisms in HIV and SIV
por: Meuwissen, PJ, et al.
Publicado: (2011)

Characterization of CD8(+) T Cell Differentiation following SIVΔnef Vaccination by Transcription Factor Expression Profiling
por: Billingsley, James M., et al.
Publicado: (2015)

Correction: Transduction of SIV-Specific TCR Genes into Rhesus Macaque CD8(+) T Cells Conveys the Ability to Suppress SIV Replication
por: Barsov, Eugene V., et al.
Publicado: (2018)

P03-09. Preserved adaptive immune responses and limited immune activation in CD4-low SIV-positive sooty mangabeys
por: Mir, KD, et al.
Publicado: (2009)

Location and Dynamics of the Immunodominant CD8 T Cell Response to SIVΔnef Immunization and SIVmac251 Vaginal Challenge
por: Sasikala-Appukuttan, Arun K., et al.
Publicado: (2013)

Correction: Characterization of CD8+ T Cell Differentiation following SIVΔnef Vaccination by Transcription Factor Expression Profiling
Publicado: (2015)

Chronic TCR-MHC (self)-interactions limit the functional potential of TCR affinity-increased CD8 T lymphocytes
por: Duong, Minh Ngoc, et al.
Publicado: (2019)

CD4 receptor diversity in chimpanzees protects against SIV infection
por: Bibollet-Ruche, Frederic, et al.
Publicado: (2019)

Endocytic sorting motif interactions involved in Nef-mediated downmodulation of CD4 and CD3
por: Manrique, Santiago, et al.
Publicado: (2017)

Persistent Low-Level Replication of SIVΔnef Drives Maturation of Antibody and CD8 T Cell Responses to Induce Protective Immunity against Vaginal SIV Infection
por: Adnan, Sama, et al.
Publicado: (2016)

CD8 T Cell Response Maturation Defined by Anentropic Specificity and Repertoire Depth Correlates with SIVΔnef-induced Protection
por: Adnan, Sama, et al.
Publicado: (2015)

Alterations in intracellular potassium concentration by HIV-1 and SIV Nef
por: Choi, Bongkun, et al.
Publicado: (2008)

Analyses of the TCR repertoire of MHC class II-restricted innate CD4(+) T cells
por: Kang, Byung Hyun, et al.
Publicado: (2015)

Correction: CD8 T Cell Response Maturation Defined by Anentropic Specificity and Repertoire Depth Correlates with SIVΔnef-induced Protection
Publicado: (2015)

CD8(+) lymphocyte control of SIV infection during antiretroviral therapy
por: Cao, Youfang, et al.
Publicado: (2018)

Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM
por: Saotome, Kei, et al.
Publicado: (2023)

Collapse of Cytolytic Potential in SIV-Specific CD8+ T Cells Following Acute SIV Infection in Rhesus Macaques
por: Roberts, Emily R., et al.
Publicado: (2016)

Characterization of Nef expression in different brain regions of SIV-infected macaques
por: Yarandi, Shadan S., et al.
Publicado: (2020)

n-3 Polyunsaturated Fatty Acids Impede the TCR Mobility and the TCR–pMHC Interaction of Anti-Viral CD8(+) T Cells
por: Lim, Younghyun, et al.
Publicado: (2020)

Distinct transcriptome profiles of Gag-specific CD8+ T cells temporally correlated with the protection elicited by SIVΔnef live attenuated vaccine
por: Lu, Wuxun, et al.
Publicado: (2017)

Human TCR-gamma+/delta+, CD8+ T lymphocytes recognize tetanus toxoid in an MHC-restricted fashion
Publicado: (1989)

Rectal HSV-2 Infection May Increase Rectal SIV Acquisition Even in the Context of SIVΔnef Vaccination
por: Guerra-Pérez, Natalia, et al.
Publicado: (2016)

The role of CD101-expressing CD4 T cells in HIV/SIV pathogenesis and persistence
por: Strongin, Zachary, et al.
Publicado: (2022)

Live Attenuated Rev-Independent Nef¯SIV Enhances Acquisition of Heterologous SIVsmE660 in Acutely Vaccinated Rhesus Macaques
por: Byrareddy, Siddappa N., et al.
Publicado: (2013)

Loss of Nef-mediated CD3 down-regulation in the HIV-1 lineage increases viral infectivity and spread
por: Mesner, Dejan, et al.
Publicado: (2020)

SIV-induced terminally differentiated adaptive NK cells in lymph nodes associated with enhanced MHC-E restricted activity
por: Huot, Nicolas, et al.
Publicado: (2021)

Profound CD4(+)/CCR5(+) T cell expansion is induced by CD8(+) lymphocyte depletion but does not account for accelerated SIV pathogenesis
por: Okoye, Afam, et al.
Publicado: (2009)

The TCR’s sensitivity to self-peptide–MHC dictates the ability of naïve CD8(+) T cells to respond to foreign antigens
por: Fulton, Ross B., et al.
Publicado: (2014)

Loss and regain of SIV control upon CD8+ cell depletion in vivo in SIV-controller macaques is not associated with efficient SIV specific CD8+ T-cells
por: Hamimi, C, et al.
Publicado: (2012)

Nef gene evolution from a single transmitted strain in acute SIV infection
por: Bimber, Benjamin N, et al.
Publicado: (2009)

GagCM9-Specific CD8(+) T Cells Expressing Limited Public TCR Clonotypes Do Not Suppress SIV Replication In Vivo
por: Vojnov, Lara, et al.
Publicado: (2011)

Haploidentical CD3(+) TCR αβ/CD19(+)–depleted HSCT for MHC class II deficiency and persistent SARS-CoV-2 pneumonitis
por: Ramanathan, Subramaniam, et al.
Publicado: (2022)

Early expression of mature αβ TCR in CD4(−)CD8(−) T cell progenitors enables MHC to drive development of T-ALL bearing NOTCH mutations
por: Laffey, Kimberly G., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_mecbgbjeqpuslu1b9dtqs7tou1