Pharmacokinetics of recombinant activated factor VII in trauma patients with severe bleeding

INTRODUCTION: Recombinant activated factor VII (rFVIIa) has been used as adjunctive therapy in trauma patients with severe bleeding. However, its pharmacokinetics profile remains unknown. METHODS: In two placebo-controlled studies in patients with blunt and penetrating trauma, the pharmacokinetics o...

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Detalles Bibliográficos
Autores principales: Klitgaard, Thomas, y Palacios, Rene Tabanera, Boffard, Kenneth D, Iau, Philip TC, Warren, Brian, Rizoli, Sandro, Rossaint, Rolf, Kluger, Yoram, Riou, Bruno
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1750999/
https://www.ncbi.nlm.nih.gov/pubmed/16859505
http://dx.doi.org/10.1186/cc4977

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