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Antimicrobial resistance and patient outcomes: the hazards of adjustment
Outcomes studies of infections with resistant bacteria often do not account appropriately for intermediate variables – events in the causal pathway between the exposure and the outcome – when controlling for confounders. We discuss how failure to distinguish between confounders and intermediate vari...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751076/ https://www.ncbi.nlm.nih.gov/pubmed/16982010 http://dx.doi.org/10.1186/cc5019 |
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author | Schwaber, Mitchell J Carmeli, Yehuda |
author_facet | Schwaber, Mitchell J Carmeli, Yehuda |
author_sort | Schwaber, Mitchell J |
collection | PubMed |
description | Outcomes studies of infections with resistant bacteria often do not account appropriately for intermediate variables – events in the causal pathway between the exposure and the outcome – when controlling for confounders. We discuss how failure to distinguish between confounders and intermediate variables can bias the analysis, and we address methods of approaching this issue. |
format | Text |
id | pubmed-1751076 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-17510762006-12-27 Antimicrobial resistance and patient outcomes: the hazards of adjustment Schwaber, Mitchell J Carmeli, Yehuda Crit Care Commentary Outcomes studies of infections with resistant bacteria often do not account appropriately for intermediate variables – events in the causal pathway between the exposure and the outcome – when controlling for confounders. We discuss how failure to distinguish between confounders and intermediate variables can bias the analysis, and we address methods of approaching this issue. BioMed Central 2006 2006-09-05 /pmc/articles/PMC1751076/ /pubmed/16982010 http://dx.doi.org/10.1186/cc5019 Text en Copyright © 2006 BioMed Central Ltd |
spellingShingle | Commentary Schwaber, Mitchell J Carmeli, Yehuda Antimicrobial resistance and patient outcomes: the hazards of adjustment |
title | Antimicrobial resistance and patient outcomes: the hazards of adjustment |
title_full | Antimicrobial resistance and patient outcomes: the hazards of adjustment |
title_fullStr | Antimicrobial resistance and patient outcomes: the hazards of adjustment |
title_full_unstemmed | Antimicrobial resistance and patient outcomes: the hazards of adjustment |
title_short | Antimicrobial resistance and patient outcomes: the hazards of adjustment |
title_sort | antimicrobial resistance and patient outcomes: the hazards of adjustment |
topic | Commentary |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751076/ https://www.ncbi.nlm.nih.gov/pubmed/16982010 http://dx.doi.org/10.1186/cc5019 |
work_keys_str_mv | AT schwabermitchellj antimicrobialresistanceandpatientoutcomesthehazardsofadjustment AT carmeliyehuda antimicrobialresistanceandpatientoutcomesthehazardsofadjustment |