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Antimicrobial resistance and patient outcomes: the hazards of adjustment

Outcomes studies of infections with resistant bacteria often do not account appropriately for intermediate variables – events in the causal pathway between the exposure and the outcome – when controlling for confounders. We discuss how failure to distinguish between confounders and intermediate vari...

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Detalles Bibliográficos
Autores principales: Schwaber, Mitchell J, Carmeli, Yehuda
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751076/
https://www.ncbi.nlm.nih.gov/pubmed/16982010
http://dx.doi.org/10.1186/cc5019
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author Schwaber, Mitchell J
Carmeli, Yehuda
author_facet Schwaber, Mitchell J
Carmeli, Yehuda
author_sort Schwaber, Mitchell J
collection PubMed
description Outcomes studies of infections with resistant bacteria often do not account appropriately for intermediate variables – events in the causal pathway between the exposure and the outcome – when controlling for confounders. We discuss how failure to distinguish between confounders and intermediate variables can bias the analysis, and we address methods of approaching this issue.
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spelling pubmed-17510762006-12-27 Antimicrobial resistance and patient outcomes: the hazards of adjustment Schwaber, Mitchell J Carmeli, Yehuda Crit Care Commentary Outcomes studies of infections with resistant bacteria often do not account appropriately for intermediate variables – events in the causal pathway between the exposure and the outcome – when controlling for confounders. We discuss how failure to distinguish between confounders and intermediate variables can bias the analysis, and we address methods of approaching this issue. BioMed Central 2006 2006-09-05 /pmc/articles/PMC1751076/ /pubmed/16982010 http://dx.doi.org/10.1186/cc5019 Text en Copyright © 2006 BioMed Central Ltd
spellingShingle Commentary
Schwaber, Mitchell J
Carmeli, Yehuda
Antimicrobial resistance and patient outcomes: the hazards of adjustment
title Antimicrobial resistance and patient outcomes: the hazards of adjustment
title_full Antimicrobial resistance and patient outcomes: the hazards of adjustment
title_fullStr Antimicrobial resistance and patient outcomes: the hazards of adjustment
title_full_unstemmed Antimicrobial resistance and patient outcomes: the hazards of adjustment
title_short Antimicrobial resistance and patient outcomes: the hazards of adjustment
title_sort antimicrobial resistance and patient outcomes: the hazards of adjustment
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751076/
https://www.ncbi.nlm.nih.gov/pubmed/16982010
http://dx.doi.org/10.1186/cc5019
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