Systemic hypothermia increases PAI-1 expression and accelerates microvascular thrombus formation in endotoxemic mice

INTRODUCTION: Hypothermia during sepsis significantly impairs patient outcome in clinical practice. Severe sepsis is closely linked to activation of the coagulation system, resulting in microthrombosis and subsequent organ failure. Herein, we studied whether systemic hypothermia accelerates microvas...

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Detalles Bibliográficos
Autores principales: Lindenblatt, Nicole, Menger, Michael D, Klar, Ernst, Vollmar, Brigitte
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751084/
https://www.ncbi.nlm.nih.gov/pubmed/17062126
http://dx.doi.org/10.1186/cc5074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751084/
https://www.ncbi.nlm.nih.gov/pubmed/17062126
http://dx.doi.org/10.1186/cc5074

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