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Systemic hypothermia increases PAI-1 expression and accelerates microvascular thrombus formation in endotoxemic mice
INTRODUCTION: Hypothermia during sepsis significantly impairs patient outcome in clinical practice. Severe sepsis is closely linked to activation of the coagulation system, resulting in microthrombosis and subsequent organ failure. Herein, we studied whether systemic hypothermia accelerates microvas...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751084/ https://www.ncbi.nlm.nih.gov/pubmed/17062126 http://dx.doi.org/10.1186/cc5074 |