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Electrostatic free energy landscapes for nucleic acid helix assembly
Metal ions are crucial for nucleic acid folding. From the free energy landscapes, we investigate the detailed mechanism for ion-induced collapse for a paradigm system: loop-tethered short DNA helices. We find that Na(+) and Mg(2+) play distinctive roles in helix–helix assembly. High [Na(+)] (>0.3...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751542/ https://www.ncbi.nlm.nih.gov/pubmed/17145719 http://dx.doi.org/10.1093/nar/gkl810 |