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A new modified thrombin binding aptamer containing a 5′–5′ inversion of polarity site
The solution structure of a new modified thrombin binding aptamer (TBA) containing a 5′–5′ inversion of polarity site, namely d((3′)GGT(5′)-(5′)TGGTGTGGTTGG(3)′), is reported. NMR and CD spectroscopy, as well as molecular dynamic and mechanic calculations, have been used to characterize the 3D struc...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751544/ https://www.ncbi.nlm.nih.gov/pubmed/17145716 http://dx.doi.org/10.1093/nar/gkl915 |