Expanding the repertoire of DNA polymerase substrates: template-instructed incorporation of non-nucleoside triphosphate analogues by DNA polymerases β and λ

We have recently shown that neither the base nor the sugar moieties of a nucleotide is an essential feature for its incorporation by DNA polymerases (pols) λ and β. Here we present the identification of novel non-nucleoside triphosphate (NNTP) derivatives belonging to three classes: (i) non-substrat...

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Detalles Bibliográficos
Autores principales: Crespan, Emmanuele, Alexandrova, Ludmila, Khandazhinskaya, Anastasiya, Jasko, Maxim, Kukhanova, Marina, Villani, Giuseppe, Hübscher, Ulrich, Spadari, Silvio, Maga, Giovanni
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1761426/
https://www.ncbi.nlm.nih.gov/pubmed/17148482
http://dx.doi.org/10.1093/nar/gkl1016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1761426/
https://www.ncbi.nlm.nih.gov/pubmed/17148482
http://dx.doi.org/10.1093/nar/gkl1016

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