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Development of a novel site-specific mutagenesis assay using MALDI-ToF MS (SSMA-MS)

We have developed and validated a novel site-specific mutagenesis assay, termed SSMA-MS, which incorporates MALDI-ToF mass spectrometry (MALDI-MS) analysis as a means of determining the mutations induced by a single DNA adduct. The assay involves ligating an adducted deoxyoligonucleotide into supF c...

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Detalles Bibliográficos
Autores principales:	McLuckie, Keith I. E., Lamb, John H., Sandhu, Jatinderpal K., Pearson, Helen L., Brown, Karen, Farmer, Peter B., Jones, Donald J. L.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2006
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1761429/ https://www.ncbi.nlm.nih.gov/pubmed/17130165 http://dx.doi.org/10.1093/nar/gkl745

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