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Strong HIV-1-Specific T Cell Responses in HIV-1-Exposed Uninfected Infants and Neonates Revealed after Regulatory T Cell Removal

BACKGROUND: In utero transmission of HIV-1 occurs on average in only 3%–15% of HIV-1-exposed neonates born to mothers not on antiretroviral drug therapy. Thus, despite potential exposure, the majority of infants remain uninfected. Weak HIV-1-specific T-cell responses have been detected in children e...

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Detalles Bibliográficos
Autores principales: Legrand, Fatema A., Nixon, Douglas F., Loo, Christopher P., Ono, Erika, Chapman, Joan M., Miyamoto, Maristela, Diaz, Ricardo S., Santos, Amélia M.N., Succi, Regina C.M., Abadi, Jacob, Rosenberg, Michael G., de Moraes-Pinto, Maria Isabel, Kallas, Esper G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762312/
https://www.ncbi.nlm.nih.gov/pubmed/17183635
http://dx.doi.org/10.1371/journal.pone.0000102