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Short and Long-Term Effects of hVEGF-A(165) in Cre-Activated Transgenic Mice
We have generated a transgenic mouse where hVEGF-A(165) expression has been silenced with loxP-STOP fragment, and we used this model to study the effects of hVEGF-A(165) over-expression in mice after systemic adenovirus mediated Cre-gene transfer. Unlike previous conventional transgenic models, this...
Autores principales: | Leppänen, Pia, Kholová, Ivana, Mähönen, Anssi J., Airenne, Kari, Koota, Suvi, Mansukoski, Hannu, Närväinen, Johanna, Wirzenius, Maria, Alhonen, Leena, Jänne, Juhani, Alitalo, Kari, Ylä-Herttuala, Seppo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762316/ https://www.ncbi.nlm.nih.gov/pubmed/17183639 http://dx.doi.org/10.1371/journal.pone.0000013 |
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