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A Proof-Of-Principle Study of Epigenetic Therapy Added to Neoadjuvant Doxorubicin Cyclophosphamide for Locally Advanced Breast Cancer
BACKGROUND: Aberrant DNA methylation and histone deacetylation participate in cancer development and progression; hence, their reversal by inhibitors of DNA methylation and histone deacetylases (HDACs) is at present undergoing clinical testing in cancer therapy. As epigenetic alterations are common...
Autores principales: | Arce, Claudia, Pérez-Plasencia, Carlos, González-Fierro, Aurora, de la Cruz-Hernández, Erick, Revilla-Vázquez, Alma, Chávez-Blanco, Alma, Trejo-Becerril, Catalina, Pérez-Cárdenas, Enrique, Taja-Chayeb, Lucia, Bargallo, Enrique, Villarreal, Patricia, Ramírez, Teresa, Vela, Teresa, Candelaria, Myrna, Camargo, Maria F., Robles, Elizabeth, Dueñas-González, Alfonso |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762324/ https://www.ncbi.nlm.nih.gov/pubmed/17183730 http://dx.doi.org/10.1371/journal.pone.0000098 |
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