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Efficient Non-Viral Ocular Gene Transfer with Compacted DNA Nanoparticles

BACKGROUND: The eye is an excellent candidate for gene therapy as it is immune privileged and much of the disease-causing genetics are well understood. Towards this goal, we evaluated the efficiency of compacted DNA nanoparticles as a system for non-viral gene transfer to ocular tissues. The compact...

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Detalles Bibliográficos
Autores principales: Farjo, Rafal, Skaggs, Jeff, Quiambao, Alexander B., Cooper, Mark J., Naash, Muna I.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762345/
https://www.ncbi.nlm.nih.gov/pubmed/17183666
http://dx.doi.org/10.1371/journal.pone.0000038

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