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Efficient Non-Viral Ocular Gene Transfer with Compacted DNA Nanoparticles
BACKGROUND: The eye is an excellent candidate for gene therapy as it is immune privileged and much of the disease-causing genetics are well understood. Towards this goal, we evaluated the efficiency of compacted DNA nanoparticles as a system for non-viral gene transfer to ocular tissues. The compact...
Autores principales: | Farjo, Rafal, Skaggs, Jeff, Quiambao, Alexander B., Cooper, Mark J., Naash, Muna I. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762345/ https://www.ncbi.nlm.nih.gov/pubmed/17183666 http://dx.doi.org/10.1371/journal.pone.0000038 |
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