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Expression of Transgenes Targeted to the Gt(ROSA)26Sor Locus Is Orientation Dependent
BACKGROUND: Targeting transgenes to a chosen location in the genome has a number of advantages. A single copy of the DNA construct can be inserted by targeting into regions of chromatin that allow the desired developmental and tissue-specific expression of the transgene. METHODOLOGY: In order to dev...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762389/ https://www.ncbi.nlm.nih.gov/pubmed/17183668 http://dx.doi.org/10.1371/journal.pone.0000004 |