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CD4(+)CD25(+)FOXP3(+) Regulatory T Cells Suppress Anti-Tumor Immune Responses in Patients with Colorectal Cancer

BACKGROUND: A wealth of evidence obtained using mouse models indicates that CD4(+)CD25(+)FOXP3(+) regulatory T cells (Treg) maintain peripheral tolerance to self-antigens and also inhibit anti-tumor immune responses. To date there is limited information about CD4(+) T cell responses in patients with...

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Detalles Bibliográficos
Autores principales:	Clarke, Sarah L., Betts, Gareth J., Plant, Andrea, Wright, Kate L., El-Shanawany, Tariq M., Harrop, Richard, Torkington, Jared, Rees, Brian I., Williams, Geraint T., Gallimore, Awen M., Godkin, Andrew J.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762416/ https://www.ncbi.nlm.nih.gov/pubmed/17205133 http://dx.doi.org/10.1371/journal.pone.0000129

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