IL-7 Up-Regulates TNF-α-Dependent Osteoclastogenesis in Patients Affected by Solid Tumor

BACKGROUND: Interleukin-7 (IL-7) is a potent regulator of lymphocyte development, which has also significant effects on bone; in fact it is a potent osteoclastogenic factor. Some human solid tumors produce high IL-7 levels, suggesting a potential IL-7 role on tumor development and progression. METHO...

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Detalles Bibliográficos
Autores principales: Roato, Ilaria, Brunetti, Giacomina, Gorassini, Eva, Grano, Maria, Colucci, Silvia, Bonello, Lisa, Buffoni, Lucio, Manfredi, Roberto, Ruffini, Enrico, Ottaviani, Davide, Ciuffreda, Libero, Mussa, Antonio, Ferracini, Riccardo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762428/
https://www.ncbi.nlm.nih.gov/pubmed/17205128
http://dx.doi.org/10.1371/journal.pone.0000124

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