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Effects of epidural lidocaine analgesia on labor and delivery: A randomized, prospective, controlled trial

BACKGROUND: Whether epidural analgesia for labor prolongs the active-first and second labor stages and increases the risk of vacuum-assisted delivery is a controversial topic. Our study was conducted to answer the question: does lumbar epidural analgesia with lidocaine affect the progress of labor i...

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Autor principal: Nafisi, Shahram
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764008/
https://www.ncbi.nlm.nih.gov/pubmed/17176461
http://dx.doi.org/10.1186/1471-2253-6-15
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author Nafisi, Shahram
author_facet Nafisi, Shahram
author_sort Nafisi, Shahram
collection PubMed
description BACKGROUND: Whether epidural analgesia for labor prolongs the active-first and second labor stages and increases the risk of vacuum-assisted delivery is a controversial topic. Our study was conducted to answer the question: does lumbar epidural analgesia with lidocaine affect the progress of labor in our obstetric population? METHOD: 395 healthy, nulliparous women, at term, presented in spontaneous labor with a singleton vertex presentation. These patients were randomized to receive analgesia either, epidural with bolus doses of 1% lidocaine or intravenous, with meperidine 25 to 50 mg when their cervix was dilated to 4 centimeters. The duration of the active-first and second stages of labor and the neonatal apgar scores were recorded, in each patient. The total number of vacuum-assisted and cesarean deliveries were also measured. RESULTS: 197 women were randomized to the epidural group. 198 women were randomized to the single-dose intravenous meperidine group. There was no statistical difference in rates of vacuum-assisted delivery rate. Cesarean deliveries, as a consequence of fetal bradycardia or dystocia, did not differ significantly between the groups. Differences in the duration of the active-first and the second stages of labor were not statistically significant. The number of newborns with 1-min and 5-min Apgar scores less than 7, did not differ significantly between both analgesia groups. CONCLUSION: Epidural analgesia with 1% lidocaine does not prolong the active-first and second stages of labor and does not increase vacuum-assisted or cesarean delivery rate.
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spelling pubmed-17640082007-01-05 Effects of epidural lidocaine analgesia on labor and delivery: A randomized, prospective, controlled trial Nafisi, Shahram BMC Anesthesiol Research Article BACKGROUND: Whether epidural analgesia for labor prolongs the active-first and second labor stages and increases the risk of vacuum-assisted delivery is a controversial topic. Our study was conducted to answer the question: does lumbar epidural analgesia with lidocaine affect the progress of labor in our obstetric population? METHOD: 395 healthy, nulliparous women, at term, presented in spontaneous labor with a singleton vertex presentation. These patients were randomized to receive analgesia either, epidural with bolus doses of 1% lidocaine or intravenous, with meperidine 25 to 50 mg when their cervix was dilated to 4 centimeters. The duration of the active-first and second stages of labor and the neonatal apgar scores were recorded, in each patient. The total number of vacuum-assisted and cesarean deliveries were also measured. RESULTS: 197 women were randomized to the epidural group. 198 women were randomized to the single-dose intravenous meperidine group. There was no statistical difference in rates of vacuum-assisted delivery rate. Cesarean deliveries, as a consequence of fetal bradycardia or dystocia, did not differ significantly between the groups. Differences in the duration of the active-first and the second stages of labor were not statistically significant. The number of newborns with 1-min and 5-min Apgar scores less than 7, did not differ significantly between both analgesia groups. CONCLUSION: Epidural analgesia with 1% lidocaine does not prolong the active-first and second stages of labor and does not increase vacuum-assisted or cesarean delivery rate. BioMed Central 2006-12-18 /pmc/articles/PMC1764008/ /pubmed/17176461 http://dx.doi.org/10.1186/1471-2253-6-15 Text en Copyright © 2006 Nafisi; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Nafisi, Shahram
Effects of epidural lidocaine analgesia on labor and delivery: A randomized, prospective, controlled trial
title Effects of epidural lidocaine analgesia on labor and delivery: A randomized, prospective, controlled trial
title_full Effects of epidural lidocaine analgesia on labor and delivery: A randomized, prospective, controlled trial
title_fullStr Effects of epidural lidocaine analgesia on labor and delivery: A randomized, prospective, controlled trial
title_full_unstemmed Effects of epidural lidocaine analgesia on labor and delivery: A randomized, prospective, controlled trial
title_short Effects of epidural lidocaine analgesia on labor and delivery: A randomized, prospective, controlled trial
title_sort effects of epidural lidocaine analgesia on labor and delivery: a randomized, prospective, controlled trial
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764008/
https://www.ncbi.nlm.nih.gov/pubmed/17176461
http://dx.doi.org/10.1186/1471-2253-6-15
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