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Effects of epidural lidocaine analgesia on labor and delivery: A randomized, prospective, controlled trial
BACKGROUND: Whether epidural analgesia for labor prolongs the active-first and second labor stages and increases the risk of vacuum-assisted delivery is a controversial topic. Our study was conducted to answer the question: does lumbar epidural analgesia with lidocaine affect the progress of labor i...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764008/ https://www.ncbi.nlm.nih.gov/pubmed/17176461 http://dx.doi.org/10.1186/1471-2253-6-15 |
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author | Nafisi, Shahram |
author_facet | Nafisi, Shahram |
author_sort | Nafisi, Shahram |
collection | PubMed |
description | BACKGROUND: Whether epidural analgesia for labor prolongs the active-first and second labor stages and increases the risk of vacuum-assisted delivery is a controversial topic. Our study was conducted to answer the question: does lumbar epidural analgesia with lidocaine affect the progress of labor in our obstetric population? METHOD: 395 healthy, nulliparous women, at term, presented in spontaneous labor with a singleton vertex presentation. These patients were randomized to receive analgesia either, epidural with bolus doses of 1% lidocaine or intravenous, with meperidine 25 to 50 mg when their cervix was dilated to 4 centimeters. The duration of the active-first and second stages of labor and the neonatal apgar scores were recorded, in each patient. The total number of vacuum-assisted and cesarean deliveries were also measured. RESULTS: 197 women were randomized to the epidural group. 198 women were randomized to the single-dose intravenous meperidine group. There was no statistical difference in rates of vacuum-assisted delivery rate. Cesarean deliveries, as a consequence of fetal bradycardia or dystocia, did not differ significantly between the groups. Differences in the duration of the active-first and the second stages of labor were not statistically significant. The number of newborns with 1-min and 5-min Apgar scores less than 7, did not differ significantly between both analgesia groups. CONCLUSION: Epidural analgesia with 1% lidocaine does not prolong the active-first and second stages of labor and does not increase vacuum-assisted or cesarean delivery rate. |
format | Text |
id | pubmed-1764008 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-17640082007-01-05 Effects of epidural lidocaine analgesia on labor and delivery: A randomized, prospective, controlled trial Nafisi, Shahram BMC Anesthesiol Research Article BACKGROUND: Whether epidural analgesia for labor prolongs the active-first and second labor stages and increases the risk of vacuum-assisted delivery is a controversial topic. Our study was conducted to answer the question: does lumbar epidural analgesia with lidocaine affect the progress of labor in our obstetric population? METHOD: 395 healthy, nulliparous women, at term, presented in spontaneous labor with a singleton vertex presentation. These patients were randomized to receive analgesia either, epidural with bolus doses of 1% lidocaine or intravenous, with meperidine 25 to 50 mg when their cervix was dilated to 4 centimeters. The duration of the active-first and second stages of labor and the neonatal apgar scores were recorded, in each patient. The total number of vacuum-assisted and cesarean deliveries were also measured. RESULTS: 197 women were randomized to the epidural group. 198 women were randomized to the single-dose intravenous meperidine group. There was no statistical difference in rates of vacuum-assisted delivery rate. Cesarean deliveries, as a consequence of fetal bradycardia or dystocia, did not differ significantly between the groups. Differences in the duration of the active-first and the second stages of labor were not statistically significant. The number of newborns with 1-min and 5-min Apgar scores less than 7, did not differ significantly between both analgesia groups. CONCLUSION: Epidural analgesia with 1% lidocaine does not prolong the active-first and second stages of labor and does not increase vacuum-assisted or cesarean delivery rate. BioMed Central 2006-12-18 /pmc/articles/PMC1764008/ /pubmed/17176461 http://dx.doi.org/10.1186/1471-2253-6-15 Text en Copyright © 2006 Nafisi; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Nafisi, Shahram Effects of epidural lidocaine analgesia on labor and delivery: A randomized, prospective, controlled trial |
title | Effects of epidural lidocaine analgesia on labor and delivery: A randomized, prospective, controlled trial |
title_full | Effects of epidural lidocaine analgesia on labor and delivery: A randomized, prospective, controlled trial |
title_fullStr | Effects of epidural lidocaine analgesia on labor and delivery: A randomized, prospective, controlled trial |
title_full_unstemmed | Effects of epidural lidocaine analgesia on labor and delivery: A randomized, prospective, controlled trial |
title_short | Effects of epidural lidocaine analgesia on labor and delivery: A randomized, prospective, controlled trial |
title_sort | effects of epidural lidocaine analgesia on labor and delivery: a randomized, prospective, controlled trial |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764008/ https://www.ncbi.nlm.nih.gov/pubmed/17176461 http://dx.doi.org/10.1186/1471-2253-6-15 |
work_keys_str_mv | AT nafisishahram effectsofepidurallidocaineanalgesiaonlaboranddeliveryarandomizedprospectivecontrolledtrial |