At-Risk and Recent-Onset Type 1 Diabetic Subjects Have Increased Apoptosis in the CD4+CD25+(high) T-Cell Fraction

BACKGROUND: In experimental models, Type 1 diabetes T1D can be prevented by adoptive transfer of CD4+CD25+ FoxP3+ suppressor or regulatory T cells. Recent studies have found a suppression defect of CD4+CD25+(high) T cells in human disease. In this study we measure apoptosis of CD4+CD25+(high) T cell...

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Detalles Bibliográficos
Autores principales: Glisic-Milosavljevic, Sanja, Waukau, Jill, Jailwala, Parthav, Jana, Srikanta, Khoo, Huoy-Jii, Albertz, Hope, Woodliff, Jeffrey, Koppen, Marilyn, Alemzadeh, Ramin, Hagopian, William, Ghosh, Soumitra
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764033/
https://www.ncbi.nlm.nih.gov/pubmed/17206281
http://dx.doi.org/10.1371/journal.pone.0000146

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