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TRPV1 antagonists attenuate antigen-provoked cough in ovalbumin sensitized guinea pigs

We examined the molecular pharmacology and in vivo effects of a TRPV1 receptor antagonist, N-(4-Tertiarybutylphenyl)-4(3-cholorphyridin-2-yl)-tetrahydro-pyrazine1(2H) – carboxamide (BCTC) on the guinea pig TRPV1 cation channel. BCTC antagonized capsaicin-induced activation and PMA-mediated activatio...

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Detalles Bibliográficos
Autores principales:	McLeod, Robbie L, Fernandez, Xiomara, Correll, Craig C, Phelps, Tara P, Jia, Yanlin, Wang, Xin, Hey, John A
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764418/ https://www.ncbi.nlm.nih.gov/pubmed/17173683 http://dx.doi.org/10.1186/1745-9974-2-10

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